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style="font-size:16px"><strong>防霉劑的“防止發霉”的應用原理</strong></div> <p class="news-th"><span>發布時間：2023/6/3 14:45:51</span> <span>閱讀次數：<script language="javascript" src="/inc/article_view.asp?id=1486"></script></span></p> </h3><hr width="100%" size="1" noshade color="#c1c1c1"> </div> <div style="width:880px; text-align:left; line-height:180%;" class="news_content_body"> <div class="nei_news"> （一）損壞細胞結構<br /> <br /> 1、損傷細胞壁：抗菌物質能競爭性抑制組成細胞壁構成物質的酶反應，從而抑制微生物細胞壁的組成。（青霉素、頭孢菌素、季銨鹽、溶菌酶堵截肽葡聚糖、醛與氨基反應）<br /> <br /> 2、損壞細胞膜：損壞細胞膜中脂質分子與蛋白質的連接，以及損壞磷脂質的分子結構；通過改變細胞膜表面電荷性質，損壞細胞膜的通透性；通過抑制磷脂質的各種成分的組成，抑制細胞膜的組成。<br /> <br /> 3、損壞蛋白質的結構：抗菌物質能使酶變性失活，能與蛋白質的巰基和氨基相互作用，損壞酶蛋白的立體構象，甚至能分解一部分蛋白質，使蛋白質鏈間的親脂鍵被損壞。<br /> <br /> （二）影響代謝作用<br /> <br /> 1、抑制酶的生機：<br /> <br /> （1）損壞酶的立體構型，使酶變性失活：防霉物質損壞酶蛋白的空間構型時，勢必會拆散其生機中心，使酶喪失生機；<br /> <br /> （2）抑制酶的生機：防霉劑能夠與酶的生機中心的氨基酸殘基的活性基-SH、-OH等，使這些活性基的化學性質發生改變，空間構型沒有變化，但是酶生機下降，甚至喪失；<br /> <br /> （3）與酶的激活劑（金屬離子）螯合，抑制酶的活性：防霉物質能夠干擾細胞中金屬的利用，從而抑制酶的生機，束縛一定空間的金屬，使微生物不能利用；也能進入微生物細胞內，束縛細胞內的金屬。<br /> <br /> 2、抑制呼吸作用：防霉物質能抑制基質的脫氫，能抑制與呼吸作用一些相關的酶，能夠抑制電子的傳遞等。<br /> <br /> （三）損壞核酸結構，影響微生物繁衍<br /> <br /> 1、產生驟變：防霉劑能夠引起染色體斷裂和重組；利用一些核苷酸的堿基類似物，使微生物細胞的組成DNA時錯誤的組入，代替正常的核苷酸，造成染色體畸變；與DNA的堿基的氨基或羥基反應，引起DNA復制時堿基順序的改變，從而引起其組成的蛋白質結構改變，酶的失活。<br /> <br /> 2、抑制染色體的分裂，影響有絲分裂：（1）能與染色體內主要物質DNA反應，使染色體在有絲分裂時不能分隔；（2）阻礙有絲分裂期間紡錘體的形成，使得子細胞核物質不能被拉向新的細胞。 </div> </div> </div> </div> <div id="right"> </div> <div class="clear"></div> </div> <article class="Main_Template ExceptPub"> <section class="Home_Products"> <header> <h3>推薦產品</h3> <span>Products</span> </header> <ul class='ProductShow'><li><a href='/Product/1832404936.html' title='鞋用防霉片'><span><img src='/images/up_images/鞋用防霉片.jpg' alt='鞋用防霉片' /></span>鞋用防霉片</a></li><li><a href='/Product/7169255541.html' title='服裝防霉片'><span><img src='/images/up_images/服裝防霉片.jpg' alt='服裝防霉片' /></span>服裝防霉片</a></li><li><a href='/Product/5069832933.html' title='光學儀器防霉片'><span><img src='/images/up_images/光學儀器防霉片.jpg' alt='光學儀器防霉片' /></span>光學儀器防霉片</a></li><li><a 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